Conditional gene knock‐down by CRE‐dependent short interfering RNAs
نویسندگان
چکیده
منابع مشابه
Conditional gene knock-down by CRE-dependent short interfering RNAs.
Short interfering RNAs (siRNAs) are short (21-23 nt) double-stranded RNAs that direct the sequence-specific degradation of corresponding mRNAs, resulting in suppression of gene activity. siRNAs are powerful tools for gene functional analysis in mammals. Chemically synthesized siRNAs permit transient gene repression but preclude inhibition of stable gene products as well as long-term phenotypic ...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2004
ISSN: 1469-221X,1469-3178
DOI: 10.1038/sj.embor.7400064